Alopecia X - Black Skin Disease in Pomeranians. German site with information on Alopecia X - Black Skin Disease in Pomeranians

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Alopecia X has been described in several breeds including Pomeranians, Keeshonden, Alaskan Malamutes, Chow Chows, and Miniature Poodles. Affected animals suffer from hair loss, which usually starts at the neck and body of the animal, whereas the head and front legs are typically spared. Additionally, darkening of the affected skin areas may also be observed. Symptoms typically show up between 1-5 years of age. We would like to investigate the genetic causes of alopecia X. For our research we need DNA samples from affected dogs as well as their healthy relatives

Category :	Pomeranian Resources :-> Pomeranian Health Resources
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Alopecia X

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What is Alopecia X ?

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Treatment of canine Alopecia X with trilostane

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Alopecia X: Aetiopathogenesis, Clinical Signs, Diagnosis and Treatment

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Alopecia X in the Keeshond

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Many young Pomeranians develope a luxurious puppy or first hair coat which fails to shed and is not replaced by an adult coat. As the puppy coat ages it breaks off and falls out and can result in a dog that is hairless over much of its body. This disease is sometimes called black skin disease, coat funk or woolly coat. It also occurs in Keeshonden and Alaskan Malamutes. Although females can have the disease, it is much more common in males. This suggests, but does not prove, that the mutation responsible for the disease is on the X chromosome. We propose to determine if a DNA marker from the canine X chromosome associates with the disease. If so, this marker could then be used to distinguish genetically normal puppies from puppies that are likely to develop the disease. This marker could also identify female puppies that will not develop the disease but are likely to pass the disease on to the next generation.

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Clinicopathologic and Morphologic Analysis of the Adrenal Gland
in Pomeranians with Non-Illness Alopecia

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Coat Funk

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